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Or, maybe Cwn is working well for your aching joints, but you come down with a cold and take an over-the-counter OTC cold medicine for your cough and sore throat.

In either case, if you are not careful, you could be setting yourself up for problems. Even OTC drugs carry a risk of side effects, and by taking two or more together you could be increasing that risk or even putting yourself in danger of an overdose. Adding acetaminophen to nonsteroidal anti-inflammatory drugs NSAIDssuch as ibuprofen or Can i take codeine with ibuprofen, can be an effective way to improve pain ibuprofeh.

In fact, in Europe there are products that combine the two. But one study shows the combination could potentially increase the risk tak gastrointestinal bleeding.

In a British study published in the Annals of the Rheumatic Wkthpatients were assigned to one of four treatment groups -- acetaminophen only, ibuprofen Can i take codeine with ibuprofen, a low dose of both acetaminophen and ibuprofen, and high dose of acetaminophen and ibuprofen — and then evaluated after 10 days and again after three months.

While the group taking the high-dose combination witu experienced the biggest improvements in pain relief, stiffness, function and quality of life at both check-ups, that pain relief came at a cost.

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At the end of the week trial, The researchers write that they are concerned that there may be a synergistic — and not just additive — effect between ibuprofen and acetaminophen in the combination pills that potentially leads to GI bleeding. Moore was not involved with the study.

But knowingly combining two different pain relievers is not the only risky practice. The same goes for acetaminophenwhich can be found in a number of OTC cold formulations, headache remedies and cough medicines.

Consuming high doses of acetaminophen — long believed not wiith irritate the GI system — also can cause GI bleeding, the British study found. Perhaps more disturbing is that an acetaminophen overdose can also lead to acute liver damage, which could be deadly.

The risk was so concerning that in the FDA asked manufacturers of prescription drugs to limit the amount of acetaminophen to mg per tablet or capsule. The FDA set the maximum codenie dose of acetaminophen at 4, mg. Many believe the daily limit should be lower — 3, mg per day.

But keeping within the limits — or even keeping up with how much you are consuming — can be difficult if you are taking more than one acetaminophen-containing product. So, what does that mean for consumers?

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Know all you can about the medications you are taking. When purchasing an OTC product, read the label for ingredients.

You should also tell your doctor about all medications you take, including over-the-counter drugs, plus when and how often you take them. Moore says.

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